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Curriculum Vitae

 

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 Elguja Miminoshvili

Home:17 Fanaskerteli St., Tbilisi, 0115, Georgia

Phone: (995-32) 366-688

Office: 77 Kostava St. Georgian Technical University, (RCSR) Tbilisi, 0115, Georgia

Phone:(995 32) 386-682

E-mail: mimino@gtu.ge    (personal)   rcsr@gtu.edu.ge        (office)

RESEARCH: Materials Science, Crystal Structure of coordination compounds, X-ray diffraction, Advanced Materials;


EDUCATION: 1965-1970 B.S. in Physics Georgian Technical University;


1993 Candidate of Sc., Tbilisi (Synthesis and Structure of the coordination compounds 3d-transitive metals with bioactive ligands);


2003 Doctor of Sc., Tbilisi (X-ray structure investigation of coordination compounds of biometals(II) with hydrazides of carbon acids, guanidine and amino guanidine made by chemical synthesis);


EXPERIMENTAL TECHNIQUES: X-ray diffraction, X-ray crystallography, Synthesis of coordination compounds of metals;


MEMBERSHIP: Member of the International Union of crystallographers (WDCr 9, 1994); Member of the New York Academy of Sciences (1999);


PROFESSIONAL APPOINTMENTS:


1994- to present: Senior Lecturer of the Chair of Physical Material Science, Georgian TU;


1988- to present: Leading Research Scientist of the Republic Center for Structure Researches, Georgian Technical University;


1984-99: Senior Lecturer of the Department Bioinorganic and Biophysical Chemistry of Tbilisi State Medical University;


1978-88: Research Scientist of the Institute of Physical and Organic Chemistry of the Academy of Sciences of Georgia;


1970-78: Assistant of the Department of Solid State Physics, Georgian TU;


 Research Interests:

 

Biologically active coordination compounds; investigation of stereochemical and structural peculiarities. The basic directions of our investigation are the chemical synthesis, study of structure, physical-chemical and biological properties of new established coordination compounds of metals (especially biologically active metals), and also search for general and individual appropriateness among conditions of synthesis, structure and properties of compounds. The synthesis is carried out and the coordination compounds of metals (M(II)=Mg, Ca, Mn, Fe, Co, Ni, Cu, Zn, Sr ) with en= NH2-CH2-CH2-NH2, eta= NH2-CH2-CH2-OH, Ф= - OOC- CH=CH-COO -, Sal= (C6H4)(OH)COO– , Ant (o-AB)= (C6H4)(NH2)COO –, p-AB=(C6H4)(NH2)COO –, GunH=C(NH2)3+, AgunH= C(NH2)2NHNH2+, AgunH2= C(NH2)2NHNH32+ enH2= NH3-CH2-CH2-NH32+, monohydrazides of carbon acids BH=(C6H4)C(O)NHNH2, m-OBH=(C6H4)(OH)C(O)NHNH2, m-NBH= (NO2)(C6H4) C(O)NHNH2, dihydrazides of carbon acids (NH2NH(O)C)2(CH2)n (n=1,2,3), polydentate L=HOOCCH2C(OH)(COOH)CH2COOH, with one or two (identical or different) acidoligands (X,Y=SO42-,Cl-,NCS-,ClO4-,I-,NO3-,NO2-,Br- ) are investigated:
  1. Ptinciples of coordination, dentatity, structural function of ligands and the stereochemical features are investigated.
  2. In metal - ligand - metal bonds the distribution of investigated ligands depends on the ratio metal : ligand and of nature of acidoligand. The compounds, containing dihydrazids are divided into two groups: I. the pairs of atoms of metal with single bis-bidentate cyclic bridges; II. the pairs of atoms of metal with double bis-bidentate cyclic bridges. The bridges of type I form grids with units with eight peaks at a ratio metal : ligand =1:2, i.e. mutually crossed four circuits, and at a ratio metal : ligand =1:1 the grids fall and the circuits of only one direction with units with six peaks turn out that corresponds polimeric gird and polimer open-chain types of structures. The bridges of type II form polymeric circuits with units with eight peaks at a ratio metal : ligand =1:2; and at a ratio 1:1 the circuits are broken off and they turn out in centrosimmetric dimers with units with six peaks. Accordingly in both cases dodecahedral units are replaced by octahedral ones.
  3. The structural type of compounds, containing hydrazids, depends on metal : ligand ratio; at a ratio 1:2 we observe polimeric foliated or polimeric chain ionic type of structures, and at a ratio 1:1 we observe polimeric chain or dimeric types of structures. The polimeric chain type compounds have only polimeric chain ionic type of structures, and dimeric type compounds have both ionic and molecular types of structures. The compounds, containing guanidin or aminoguanidin cations have ionic island type, and the compounds with the general formula [M(AgunH)2Cl4] have molecular island type structures.
  4. In the investigated structures the following coordination numbers in polihedron of metals are observed: 4, 6, 8 and 9, also octahedrons received with two tridentate ligands and their isomers. Coordination polihedron with coordination number 8 are chord's dodecahedron with distortions to the direction of an antiprism or trigonal prism with two tops. The polihedrons with coordination number 6 are more or less deformed octahedrons. In cases of compounds with hydrazids, polihedrons form cis isomers in relation to monodentate ligands. In the compounds, containing guanidin or aminoguanidin, with coordination number 4 are observed tetrahedrons, and with coordination number 6 - are observed octahedrons, both "ideal" and deformed up to tetragonal bipiramides. Coordination polihedron - bipiramides are observed in the compounds with ligands which differ by dentatity and volume. In the compounds with two tridentate ligands coordination polihedrons are observed - octahedron (asym - cis and sym - cis isomers).
  5. In the compounds of cobalt, containing benzoilhydrazin and guanidin (or aminoguanidin) are found out antispasmodic and antidote properties against cyanides.
Except of the above, the coordination compounds of the above mentioned metals with another ligands are synthesized and investigated as well. For instance, with Tm=C13N2OH20, Lid= C12N2OH18, Nov=C13N2O2H21, sulpha drugs, inhibitors (DNB=C7H3N2O6 ), and using the different solvents (DMSO=C2H6OS, DMFA=C2H6NOCH, etc.).

 

PUBLICATIONS: 143 Scientific articles, 8 inventions, 1 monograph, 3 guide;

  1. G.V. Guliaev, E.B.Miminoshvili, T.A.Peradze. Hardening at phase transformations in titanic alloys (VТ-16, VТ-30) Bulletin of Georgian Polytechnic Institute, IV, 1973, pp.123-128.
  2. А.Е.Shvelashvili, E.B.Miminoshvili, R.М.Vashakidze et al. X-Ray structure investigation of some crystals of dehydrate of tetraakvomonoethylenediaminenickel(II) sulphate. Bulletin of the Georgian Academy of Sciences N3, 1979, pp. 601-604.
  3. А.Е.Shvelashvili, R.I.Machoshvili, E.B.Miminoshvili, B.M.Shedrin et al. Investigation of the structure of compound of zine sulfate with malonic acid dihydrazide. Russian Journal of Chemistry. V.25, N7, 1980, pp.1779-1783.
  4. А.Е.Shvelashvili, E.B.Miminoshvili, E.N. Zedelashvili et al. Study of complexation in system Ni(II)-HisH. Bulletin of the Georgian Academy of Sciences, V.116, N3, 1984, pp. 601-604.
  5. The stereochemistry of coordination compounds of some metals with the carbonic acid dihydrazides А.Е.Shvelashvili, T.O.Bardosanidze E.B.Miminoshvili. "Metsniereba", Tbilisi, 1987,108 p.
  6. E.Kutelia, D.Asatiani, T. Dzigrashvili, E.Miminoshvili, еt al. Influence of thin features of structure on resist and elastic properties of high temperature superconductors. ФНТ, V.15, №9, 1989, pp.926-932.
  7. A.E.Shvelashvili, T.O.Vardosanidze, E.B.Miminoshvili et al. Compuranive Stereochemistri of Some Coordination Compounds of S-and D-elements with Dehidrazides of Carbonic Acids.Twelet Europeun Cristallografic Meeting, Moscow, 20-29 august, 1989, V.2, p.314
  8. A.E.Shvelashvili, E.B.Miminoshvili, T.O.Vardosanidze et al. Crystal and molecular structure of diakvodirodanodimetooksibenzoilhydrazincobalt(II) Coordination Chemistry, V.16 , N 12, 1990 , pp. 1657-1660.
  9. Practical guide of X-ray structural analysis of the chemical substances. A.E.Shvelashvili, E.B. Miminoshvili T.O. Vardosanidze."Ganatleba", Tbilisi, 1991,180 p.
  10. E.Kutelia, D.Asatiani, E.B.Miminoshvili, T.Kukava еt al.On the nature of 200o C peak of Internal Friction Y-Ba-Cu-O-type NTSC ceramics. 10-International Symposium on Exoelecron Emission and Application, Tbilisi, 15-19 October 1991.
  11. А.Е.Shvelashvili, E.B.Miminoshvili,T.O.Vardosanidze et al. Синтез и строение комплексов типа M(enH2)(SO4)2H2O, где M=Co(II), Mn(II), Fe(II), Ni(II) и Cu(II). Bulletin of the Georgian Academy of Sciences, V.18, N2, 1992, pp. 96-100.
  12. E.B.Miminoshvili, А.Е.Shvelashvili, T.O.Vardosanidze. Guanidinium Tetrachlorocobaltate(II): X-ray Crystallography .Russian Journal of Chemistry. V.41, N12, 1996, pp.1960-1962.
  13. G.Beradze, R.Gvetadze, E.Kutelia, N.Khidasheli E.Miminoshvili. Obtaining of High-Strong Cast-Iron wijh deformable Graphite Inclusions and Martensite-and Beinite-strengt-hend Matrix the Third ASM International Conference: Synthesis, Processing and Modeling of Advanced Materials, Paris, France, 25-27 June 1997.
  14. А.Е.Shvelashvili, E.B.Miminoshvili, V.K.Bel’skii, T.O.Vardosanidze. Crystal and Molecular Structure of Bis(aminoguanidinium)tetrachloro cobalt (II). Russian Journal of Chemistry. V.43, N2, 1998, pp.201-203.
  15. А.Е.Shvelashvili † , E.B.Miminoshvili, V.K.Bel’skii et al. Crystal Structure of Aminoguanidinium Hexachlorocobaltate . Russian Journal of Chemistry. V.44, N2, 1999, pp.198-200.
  16. А.Е.Shvelashvili † , E.B.Miminoshvili, V.K.Bel’skii, E.R.Kuteliya et al. X-Ray structure investigation of some citrate metalates. Georgian engineering news, 2000, № 3, pp.94-99.
  17. I.G.Naxucrishvili, D.A. Jishiashvili, E.B.Miminoshvili and M.A.Mushkudiani. Preparation of Ge3N4 Films on the Germanium Surface. Inorganic Materials. V. 36, № 10, 2000, pp.1-2
  18. А.Е.Shvelashvili † , E.B.Miminoshvili, V.K.Bel’skii, K.D.Amirkhanashvili et al. Crystalline and Molecular Structure of [Cu2(CH3COO)2 (DNB)2(OH2)4)2H2O. Georgian engineering news, 2001, № 1, pp.105-110.
  19. А.Е.Shvelashvili † , E.B.Miminoshvili, V.K.Bel’skii, E.R.Kuteliya et al. Crystal and Molecular Structure of Guanidinium Dicitratozincate. Russian Journal of Chemistry. V.46, N9, 2001, pp. 1345-1347.
  20. А.Shvelashvili †, M. Tskitishvili, E.Miminoshvili, K.Amirkhanashvili et al. Synthesis and Crystal Structure of MgF211H2O. Bulletin of the Georgian Academy of Sciences. V. 163, N1, 2001, pp. 74-77.
  21. А.Е.Швелашвили †, Э. Б. Миминошвили, Л.А.Беридзе, К.Э. Миминошвили. Особенности упаковки струк­турных единиц в фумарат-ион содержащих кристаллических веществах. Georgian engineering news,          № 1, 2002, c. 82-83.­
  22. E. B. Miminoshvili, A. N. Sobolev, T. N. Sakvarelidze, K. E. Miminoshvili & E. R. Kutelia (2003). Diaquabis(dimethyl sulfoxide)bis(3,5-dinitrobenzoato)zinc(II) and the synthesis of the Cu, Ni and Co analogs. Acta Cryst. C59, m118-m120
  23. A. N. Sobolev, E. B. Miminoshvili, K. E. Miminoshvili & T. N. Sakvarelidze (2003). Cobalt diacetate tetrahydrate. Acta Cryst. E59, m836-m837.
  24. E. B. Miminoshvili, A. N. Sobolev, K. E. Miminoshvili & T. N. Sakvarelidze (2004). Bis(piperidinium) trans-dichlorobis(3,5-dinitrobenzoato)zincate(II). Acta Cryst. E60, m319-m321.
  25. E. B. Miminoshvili, K. E. Miminoshvili & A. N. Sobolev (2005). Diaquabis(dimethyl sulfoxide)bis(2,4-dinitrobenzoato)cobalt(II). Acta Cryst. E61, m775-m777.
  26. Э. Б. Миминошвили, К.Э. Миминошвили, А.Н. Соболев, Л.А. Беридзе, Э.Р. Кутелия. Синтез и структура моно­ги­д­рата бис(о-гидро­кси­бен­зо­ата)бис(1,2диамин­оэтан)­ме­ди(II) и бис(о-аминобен­зо­ата) транс-диаква­бис(1,2ди­­­­мин­оэтан)­ме­ди(II). Структурная химия. 2005, Т. 46. №3, Май-июнь, С. 573-578.
  27. Э. Б. Миминошвили, К.Э. Миминошвили, В.К. Бельский, С.Р.Зазашвили Т. Н.Сакварелидзе. Кристаллическая и молеку­ляр­ная структура дицитра­то­феррата (II) гуанидиния. Структурная химия. 2005, Т. 46. №6, Ноябрь-декабрь, С. 1128-1132
  28. Э. Б. Миминошвили, К.Э. Миминошвили, С.Р.Зазашвили, Л.А. Беридзе. Синтез и структура дигидрата нитрата транс-диаква-бис(3- гидрок­си­бен­зоилгидра­зин)­меди(II). Структурная химия. 2006, Т. 47. №6, Ноябрь-декабрь, С. 1196-1200.
  29. Э. Б. Миминошвили, Т.О. Вардосанидзе, Л.А. Беридзе, К.Э. Миминошвили. Структура тетрагидрата бис­(ге­к­­са­метилентетрамин). Georgian engineering news, 2007, № 4, с. 61- 63
  30. Э. Б. Миминошвили, К.Э. Миминошвили, С.Р.Зазашвили, Л.А. Беридзе. Синтез и структура гидрата суль­­­фата транс-диаква-бис(3- гид­ро­­к­си­бен­зоилгидра­­зин)­­ме­­ди(II). Структурная химия. 2008, Т. 49. № 2, Март – апрель, С. 347-352.
  31. Э. Б. Миминошвили. Гидразидикомплексы металлов. Структурная химия. При­ложе­ние  посвяще­нный 100-летию со дня рождения акаде­мика Г.Б. Бокий. 2009, Т. 50 . C. 174-181.
  32. Э. Б. Миминошвили, К.Э. Миминошвили, Л.А. Беридзе, С.Р.Зазашвили. Рентгенографи­чес­кое исс­ле­до­­вание M(Aet)2•11H2O (M(II) =Sr, Ba) и струк­тура [Sr(Aet)(OH2)5](Aet)•3H2O. Структурная химия. 2010, Т. 51 № 1, Январь-февраль, C. 186- 191